I thought that this is a great article to again, illustrate the point that even though we’re dealing with the one type of bacteria, they exhibit different susceptibilities to antibiotics. The second and very important point is that antibiotic resistance formation is a real deal and that we should practice judicious use of it, especially in the ornamental fish industry.
NB: For a run down of this bacteria’s nomenclature, click on this link, to jump to my previous post.
| Journal of Fish Diseases |
| Volume 36, Number 1 (January 2013) |
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Antimicrobial susceptibility pattern of Flavobacterium columnare isolates collected worldwide from 17 fish species |
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Authors: |
A M Declercq, F Boyen, W den Broeck, P Bossier, A Karsi, F Haesebrouck, A Decostere |
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Author Affiliations: |
| no affiliations available |
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Source: |
Journal of Fish Diseases, Volume 36, Number 1 (January 2013) |
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Page Numbers: |
45 – 55 |
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Available Full Text: |
| Full Text: |
Subscription Required to view full text |
| Format: |
PDF |
| Size: |
unknown |
| Location: |
Publisher’s Site |
| Authentication: |
EBSCOhost EJS |
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Abstract: |
Flavobacterium columnareis the causative agent of columnaris disease in diverse fish species worldwide. Although columnaris is an important disease, the antimicrobial susceptibility pattern of F. columnareis not well studied. Thus, the purpose of this study was to test the in vitro antimicrobial susceptibility of 97 F. columnare isolates collected worldwide between 1987 and 2011 from 17 fish species. The broth microdilution technique was utilized for reliable testing of these fastidious organisms. None of the isolates displayed acquired resistance to florfenicol, gentamicin, ormetoprim-sulfadimethoxine and trimethoprim-sulfamethoxazole. Acquired resistance to chloramphenicol was detected in 1%, to nitrofuran in 5%, to oxytetracycline in 11% and to enrofloxacin, flumequine and oxolinic acid in 10%, 16% and 16% of the isolates, respectively, as reflected by a bimodal or trimodal distribution of their minimum inhibitory concentrations (MICs). One isolate showed acquired resistance towards several antimicrobial agents including erythromycin. Another isolate revealed acquired resistance towards – amongst others – ampicillin. The isolates displaying acquired resistance originated from ornamental fish species or Vietnamese catfish, except for two isolates coming from wild channel catfish in which acquired resistance was encountered towards oxytetracycline only. Fifty per cent of the resistant isolates from ornamental fish were shown to have acquired resistance against three classes of antimicrobial agents, assigning these isolates as multiple resistant. These data might indicate less prudent use of antimicrobials especially in ornamental fish species. |
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Citation: |
A M Declercq, F Boyen, W den Broeck, P Bossier, A Karsi, F Haesebrouck, A Decostere . Antimicrobial susceptibility pattern of Flavobacterium columnareisolates collected worldwide from 17 fish species. Journal of Fish Diseases, Volume 36, Number 1 (January 2013), pp. 45-55, ; |
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URL: |
http://ejournals.ebsco.com/direct.asp?ArticleID=4677B3555F70B2F9D1F3 |
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Do you think invitro is that reliable, as wouldn’t the age, length of time fish had disease & it’s immunity have an impact on the real out come ?
Water quality & temp as well? Also, is it true that columnaris goes internal, so is internal meds also a factor ?
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There are many factors that come into play when treating fish diseases. Temperature plays a major role as it affects the fish immune system. However, if the bacteria has resistance to a particular antimicrobial you’re using, then all other factors may not change the outcome. The outcome would be ineffective therapy, leading to the demise of the individual fish or continued high mortalities in the stock. This is why it’s important to run a bacterial culture and antibiotic sensitivity panel when investigating bacterial diseases in fish.
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