Just as they have a method for detecting drug resistance in bacteria against antibiotics, researchers have found a way of doing the same for this parasite, the sea louse, that plagues the salmon industry in the north.
The reasons why it’s important to test for such things are so that you know your treatment will work, you won’t wasting your money on ineffective treatment, and you’re not helping
to select for drug resistant pathogens.
Read more below.
From: “Dr. David Scarfe”
Date: 29 August 2013 3:04:09 AWST
Subject: AquaVetMed e-News: PCR approach for detecting sealice resistance to pyrethroids and organophosphates
August 28, 2013
New Approach for Detecting Sea Lice Resistance to Pyrethroids and Organophosphates
Norway – Recent research by the Sea Lice Research Centre (SLRC) has found new methods for detecting resistant sea lice using PCR technology. Partnering with the University of Bergen, the Norwegian School of Veterinary Science and PatoGen Analysis, SLRC published results regarding new methods for detection of single nucleotide polymorphisms associated with resistance towards pyrethroids and organophosphates in salmon lice.
PatoGen developed a real-time PCR-analysis that have been validated and tested on a selection of laboratory and field strains. The analysis differentiates between the genetic variants identified by genome sequencing, and correlate with results from bioassays regarding sensitivity to the relevant insecticide.
“Efficient and sensitive methods for diagnosing resistance are crucial in order to manage and control drug resistance. Early detection of reduced sensitivity to a chemical can enable effective countermeasures to be enforced at a time point when these have a greater possibility of being effective,” said SLRC. “Therefore, accurate and speedy identification of resistant L. salmonis is crucial. “Detection of resistance prior to treatment, and the use of such analysis after treatment to evaluate treatment efficacy constitutes an important determinant for the integrated pest management in the aquaculture industry.”
For more information see http://www.slrc.no/results/new-products and http://www.slrc.no/files/2012/06/SLRC-Annual-Report-2012.pdf.
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