| Journal of Fish Diseases | |||||||||||||||||
| Volume 35, Number 11 (November 2012) | |||||||||||||||||
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Preliminary success using hydrogen peroxide to treat Atlantic salmon, Salmo salar L., affected with experimentally induced amoebic gill disease (AGD) | ||||||||||||||||
| Authors: | M B Adams, P B B Crosbie, B F Nowak | ||||||||||||||||
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| Source: | Journal of Fish Diseases, Volume 35, Number 11 (November 2012) | ||||||||||||||||
| Page Numbers: | 839 – 848 | ||||||||||||||||
| Available Full Text: |
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| Abstract: | Currently, the only effective and commercially used treatment for amoebic gill disease (AGD) in farmed Tasmanian Atlantic salmon is freshwater bathing. Hydrogen peroxide (H2O2), commonly used throughout the aquaculture industry for a range of topical skin and gill infections, was trialled in vitroand in vivoto ascertain its potential as an alternative treatment against AGD. Under in vitroconditions, trophozoites of Neoparamoeba peruranswere exposed to three concentrations of H2O2in sea water (500, 1000 and 1500 mg L-1) over four durations (10, 20, 30 and 60 min) each at two temperatures (12 and 18 °C). Trophozoite viability was assessed immediately post-exposure and after 24 h. A concentration/duration combination of 1000 mg L-1for >10 min demonstrated potent amoebicidal activity. Subsequently, Atlantic salmon mildly affected with experimentally induced AGDwere treated with H2O2at 12 and 18 °C for 15 min at 1250 mg L-1and their re-infection rate was compared to freshwater-treated fish over 21 days. Significant differences in the percentage of filaments affected with hyperplastic lesions (in association with amoebae) and plasma osmolality were noted between treatment groups immediately post-bath. However, the results were largely equivocal in terms of disease resolution over a 3-week period following treatment. These data suggest that H2O2treatment in sea water successfully ameliorated a clinically light case of AGDunder laboratory conditions. | ||||||||||||||||
| Citation: | M B Adams, P B B Crosbie, B F Nowak . Preliminary success using hydrogen peroxide to treat Atlantic salmon, Salmo salar L., affected with experimentally induced amoebic gill disease (AGD). Journal of Fish Diseases, Volume 35, Number 11 (November 2012), pp. 839-848, <http://ejournals.ebsco.com/direct.asp?ArticleID=4806A1B1E8B8F7759199> | ||||||||||||||||
| URL: | http://ejournals.ebsco.com/direct.asp?ArticleID=4806A1B1E8B8F7759199 | ||||||||||||||||
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