Nemo faces an acid test in real-life movie sequel.

Townsville-based James Cook University researcher Phillip Munday and his team found clown fish, as well as damsel fish and open-water predators like tuna and spanish mackerel, suffered adverse effects under high acidity.

They said laboratory studies showed increased acid levels affected the main neuro-transmitters in fish brains, causing a malfunction in the sense of smell, hearing and perception of risk, and an increased tendency to stray from safe reef areas.

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