| Aquaculture |
| Volume 343, Number 3 (April 2012) |
 |
Vaccination effect of liposomes entrapped whole cell bacterial vaccine on immune response and disease protection in Epinephelus bruneusagainst Vibrio harveyi |
|
|
|
Authors: |
Ramasamy Harikrishnan, Ju-Sang Kim, Chellam Balasundaram, Moon-Soo Heo |
|
Author Affiliations: |
| no affiliations available |
|
|
Source: |
Aquaculture, Volume 343, Number 3 (April 2012) |
|
Page Numbers: |
69 – 74 |
|
Available Full Text: |
| Full Text: |
Subscription Required to view full text |
| Format: |
PDF |
| Size: |
Unknown |
| Location: |
Publisher’s Site |
| Authentication: |
Publisher’s Site |
|
|
|
|
Abstract: |
The protective efficacy of liposomes-entrapped with whole cell bacterial vaccine (WCV) on immune response and protection against Vibrio harveyiinfection in Epinephelus bruneuswas investigated at weeks 1, 2, and 4. The cumulative mortality was 25% in WCV immunized fish whereas it was 35% and 40% with activated whole cell V. harveyialone (WC) or liposome alone against pathogen; the mortality was 90% in non-immunization fish against pathogen. Total protein significantly increased in WCV and WC groups on weeks 2 and 4. The albumin, globulin, and albumin:globulin ratio significantly increased in WCV and WC groups on week 4. The antibody titres significantly increased in fish immunized with liposomes-entrapped WCV from weeks 1 to 4 where as in WC group only on week 4. The phagocytic activity significantly enhanced in liposomes-entrapped WCV group on weeks 1 and 2 and all other immunized groups on week 4. The complement activity was significantly enhanced in liposomes-entrapped WCV and WC immunized groups on weeks 2 and 4. However, the lysozyme activity significantly was enhanced in all immunization groups from weeks 1 to 4. These results suggest that fish immunized with liposomes-entrapped WCV and WC alone have the potential to modulate the immune system affording increased protection against V. harveyi infection in kelp grouper. |
|
Citation: |
Ramasamy Harikrishnan, Ju-Sang Kim, Chellam Balasundaram, Moon-Soo Heo . Vaccination effect of liposomes entrapped whole cell bacterial vaccine on immune response and disease protection in Epinephelus bruneusagainst Vibrio harveyi. Aquaculture, Volume 343, Number 3 (April 2012), pp. 69-74, <http://ejournals.ebsco.com/direct.asp?ArticleID=41C497B3B29BB9CA8C0D> |
|
URL: |
http://ejournals.ebsco.com/direct.asp?ArticleID=41C497B3B29BB9CA8C0D |
Published by TheFishVet - Richmond's School of Fish
Aquatic veterinary medicine, pathology and educational services for fish.
A repository for useful information and events.
View all posts by TheFishVet - Richmond's School of Fish
